TOLUENE
MSDS Number: T3913 --- Effective Date: 12/08/96
1. Product Identification
Synonyms: Methylbenzene; Toluol; Phenylmethane
CAS No.: 108-88-3
Molecular Weight: 92.14
Chemical Formula: C6H5-CH3
Product Codes:
J.T. Baker:
5375, 5584, 5809, 5812, 9336, 9351, 9364, 9456,
9457, 9459, 9460, 9462, 9466, 9472, 9476
Mallinckrodt:
4483, 8091, 8092, 8604, 8605, 8608, 8610, 8611,
V560
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Toluene 108-88-3 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
POISON! DANGER! HARMFUL OR FATAL IF SWALLOWED. HARMFUL IF INHALED OR
ABSORBED THROUGH SKIN. VAPOR HARMFUL. FLAMMABLE LIQUID AND VAPOR. MAY
AFFECT LIVER, KIDNEYS, BLOOD SYSTEM, OR CENTRAL NERVOUS SYSTEM. CAUSES
IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 2 - Moderate
Flammability Rating: 3 - Severe (Flammable)
Reactivity Rating: 0 - None
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES; CLASS B
EXTINGUISHER
Storage Color Code: Red (Flammable)
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Potential Health Effects
----------------------------------
Inhalation:
Inhalation may cause irritation of the upper respiratory tract. Symptoms of
overexposure may include fatigue, confusion, headache, dizziness and
drowsiness. Peculiar skin sensations (e. g. pins and needles) or numbness
may be produced. Very high concentrations may cause unconsciousness and
death.
Ingestion:
Swallowing may cause abdominal spasms and other symptoms that parallel
over-exposure from inhalation. Aspiration of material into the lungs can
cause chemical pneumonitis, which may be fatal.
Skin Contact:
Causes irritation. May be absorbed through skin.
Eye Contact:
Causes severe eye irritation with redness and pain.
Chronic Exposure:
Reports of chronic poisoning describe anemia, decreased blood cell count
and bone marrow hypoplasia. Liver and kidney damage may occur. Repeated or
prolonged contact has a defatting action, causing drying, redness,
dermatitis. Exposure to toluene may affect the developing fetus.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or impaired liver or kidney
function may be more susceptible to the effects of this substance.
Alcoholic beverage consumption can enhance the toxic effects of this
substance.
4. First Aid Measures
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. CALL A PHYSICIAN
IMMEDIATELY.
Ingestion:
Aspiration hazard. If swallowed, DO NOT INDUCE VOMITING. Give large
quantities of water. Never give anything by mouth to an unconscious person.
Get medical attention immediately. If vomiting occurs, keep head below
hips to prevent aspiration into lungs.
Skin Contact:
In case of contact, immediately flush skin with plenty of soap and water
for at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse. Call a physician immediately.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes,
lifting lower and upper eyelids occasionally. Get medical attention
immediately.
5. Fire Fighting Measures
Fire:
Flash point: 7C (45F) CC
Autoignition temperature: 422C (792F)
Flammable limits in air % by volume:
lel: 3.3; uel: 19
Flammable liquid and vapor!
Dangerous fire hazard when exposed to heat or flame. Vapors can flow along surfaces to distant ignition source and flash back.
Explosion:
Above flash point, vapor-air mixtures are explosive within flammable limits
noted above. Contact with strong oxidizers may cause fire or explosion.
Sensitive to static discharge.
Fire Extinguishing Media:
Dry chemical, foam or carbon dioxide. Water may be used to flush spills
away from exposures and to dilute spills to non-flammable mixtures.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode. Water spray may be used to
keep fire exposed containers cool.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition. Wear
appropriate personal protective equipment as specified in Section 8.
Isolate hazard area. Keep unnecessary and unprotected personnel from
entering. Contain and recover liquid when possible. Use non-sparking tools
and equipment. Collect liquid in an appropriate container or absorb with an
inert material (e. g., vermiculite, dry sand, earth), and place in a
chemical waste container. Do not use combustible materials, such as saw
dust. Do not flush to sewer! If a leak or spill has not ignited, use water
spray to disperse the vapors, to protect personnel attempting to stop leak,
and to flush spills away from exposures. US Regulations (CERCLA) require
reporting spills and releases to soil, water and air in excess of
reportable quantities. The toll free number for the US Coast Guard National
Response Center is (800) 424-8802.
J. T. Baker SOLUSORB(tm) solvent adsorbent is recommended for
spills of this product.
7. Handling and Storage
Protect against physical damage. Store in a cool, dry well-ventilated
location, away from any area where the fire hazard may be acute. Outside or
detached storage is preferred. Separate from incompatibles. Containers
should be bonded and grounded for transfers to avoid static sparks. Storage
and use areas should be No Smoking areas. Use non-sparking type tools and
equipment, including explosion proof ventilation. Containers of this
material may be hazardous when empty since they retain product residues
(vapors, liquid); observe all warnings and precautions listed for the
product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
Toluene:
- OSHA Permissible Exposure Limit (PEL):
200 ppm (TWA); 300 ppm (acceptable ceiling conc.); 500 ppm (maximum conc.).
- ACGIH Threshold Limit Value (TLV):
50 ppm (TWA) skin, A4 - Not Classifiable as a Human Carcinogen.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee
exposures below the Airborne Exposure Limits. Local exhaust ventilation is
generally preferred because it can control the emissions of the contaminant
at its source, preventing dispersion of it into the general work area.
Please refer to the ACGIH document, Industrial Ventilation, A Manual of
Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, a half-face organic vapor respirator may
be worn for up to ten times the exposure limit or the maximum use
concentration specified by the appropriate regulatory agency or respirator
supplier, whichever is lowest. A full-face piece organic vapor respirator
may be worn up to 50 times the exposure limit or the maximum use
concentration specified by the appropriate regulatory agency or respirator
supplier, whichever is lowest. For emergencies or instances where the
exposure levels are not known, use a full-face piece positive-pressure,
air-supplied respirator. WARNING: Air-purifying respirators do not protect
workers in oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat,
apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is
possible. Maintain eye wash fountain and quick-drench facilities in work
area.
9. Physical and Chemical Properties
Appearance:
Clear, colorless liquid.
Odor:
Aromatic benzene-like.
Solubility:
0.05 gm/100gm water @ 20C (68F).
Specific Gravity:
0.86 @ 20C / 4 C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
111C (232F)
Melting Point:
-95C (-139F)
Vapor Density (Air=1):
3.14
Vapor Pressure (mm Hg):
22 @ 20C (68F)
Evaporation Rate (BuAc=1):
2.24
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage. Containers may burst
when heated.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Heat, flame, strong oxidizers, nitric and sulfuric acids, chlorine,
nitrogen tetraoxide; will attack some forms of plastics, rubber, coatings.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
11. Toxicological Information
Toxicological Data:
Oral rat LD50: 636 mg/kg; skin rabbit LD50: 14100 uL/kg; inhalation rat
LC50: 49 gm/m3/4H; Irritation data: skin rabbit, 500 mg, Moderate; eye
rabbit, 2 mg/24H, Severe. Investigated as a tumorigen, mutagen,
reproductive effector.
Reproductive Toxicity:
Has shown some evidence of reproductive effects in laboratory animals.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Toluene (108-88-3) No No 3
12. Ecological Information
Environmental Fate:
When released into the soil, this material may evaporate to a moderate
extent. When released into the soil, this material is expected to leach
into groundwater. When released into the soil, this material may biodegrade
to a moderate extent. When released into water, this material may evaporate
to a moderate extent. When released into water, this material may
biodegrade to a moderate extent. When released into the air, this material
may be moderately degraded by reaction with photochemically produced
hydroxyl radicals. When released into the air, this material is expected to
have a half-life of less than 1 day. This material is not expected to
significantly bioaccumulate. This material has a log octanol-water
partition coefficient of less than 3.0. Bioconcentration factor = 13.2
(eels).
Environmental Toxicity:
This material is expected to be toxic to aquatic life. The LC50/96-hour
values for fish are between 10 and 100 mg/l.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be handled as
hazardous waste and sent to a RCRA approved incinerator or disposed in a
RCRA approved waste facility. Processing, use or contamination of this
product may change the waste management options. State and local disposal
regulations may differ from federal disposal regulations.
Dispose of container and unused contents in accordance with federal, state
and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: TOLUENE
Hazard Class: 3
UN/NA: UN1294
Packing Group: II
Information reported for product/size: 390LB
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: TOLUENE
Hazard Class: 3.2
UN/NA: UN1294
Packing Group: II
Information reported for product/size: 390LB
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Toluene (108-88-3) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Toluene (108-88-3) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Toluene (108-88-3) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Toluene (108-88-3) 1000 U220 No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: Yes
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Pure / Liquid)
WARNING:
THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE STATE OF
CALIFORNIA TO CAUSE BIRTH DEFECTS OR OTHER REPRODUCTIVE HARM.
Australian Hazchem Code: 3[Y]E
Poison Schedule: S6
WHMIS:
This MSDS has been prepared according to the hazard criteria of
the Controlled Products Regulations (CPR) and the MSDS contains
all of the information required by the CPR.
16. Other Information
NFPA Ratings:
Health: 2 Flammability: 3 Reactivity: 0
Label Hazard Warning:
POISON! DANGER! HARMFUL OR FATAL IF SWALLOWED. HARMFUL IF INHALED OR ABSORBED
THROUGH SKIN. VAPOR HARMFUL. FLAMMABLE LIQUID AND VAPOR. MAY AFFECT LIVER,
KIDNEYS, BLOOD SYSTEM, OR CENTRAL NERVOUS SYSTEM. CAUSES IRRITATION TO SKIN,
EYES AND RESPIRATORY TRACT.
Label Precautions:
Keep away from heat, sparks and flame.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Avoid breathing vapor.
Avoid contact with eyes, skin and clothing.
Label First Aid:
Aspiration hazard. If swallowed, DO NOT INDUCE VOMITING. Give large
quantities of water. Never give anything by mouth to an unconscious person.
If vomiting occurs, keep head below hips to prevent aspiration into lungs. If
inhaled, remove to fresh air. If not breathing, give artificial respiration.
If breathing is difficult, give oxygen. In case of contact, immediately flush
eyes or skin with plenty of water for at least 15 minutes. Remove
contaminated clothing and shoes. Wash clothing before reuse. In all cases
call a physician immediately.
Product Use:
Laboratory Reagent.
Revision Information:
New 16 section MSDS format, all sections have been revised.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or accuracy.
This document is intended only as a guide to the appropriate precautionary
handling of the material by a properly trained person using this product.
Individuals receiving the information must exercise their independent judgment
in determining its appropriateness for a particular purpose. MALLINCKRODT
BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED,
INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE
PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC.
WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
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Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)